A comparison of plasma polymorphonuclear leucocyte elastase levels in obese and lean individuals

E. Adeyemi, S. Benedict, Abdishakur Abdulle

    Research output: Contribution to journalArticle

    Abstract

    Increased release of polymorphonuclear leucocyte (PMNL) elastase, when the PMNLs are activated, can damage tissues in vivo. It was postulated that PMNL elastase might have a tissue-remodelling effect in the body and that obese individuals might have less PMNL elastase activity than lean individuals. To test this hypothesis, plasma PMNL elastase levels were determined in 70 obese individuals and 30 lean normal controls. The PMNL elastase levels (determined by enzyme-linked immunosorbent assay) in the obese group (median 36.2 ng/ml) did not differ significantly from those in the lean healthy controls (32.6 ng/ml; P = 0.5).

    Original languageEnglish (US)
    Pages (from-to)252-256
    Number of pages5
    JournalJournal of International Medical Research
    Volume26
    Issue number5
    DOIs
    StatePublished - Jan 1 1998

    Fingerprint

    Leukocyte Elastase
    Plasmas
    Tissue
    Immunosorbents
    Assays
    Enzyme-Linked Immunosorbent Assay
    Enzymes

    Keywords

    • Cathepsin G
    • Elastase
    • Myeloperoxidase
    • Obesity
    • Polymorphonuclear leucocyte

    ASJC Scopus subject areas

    • Biochemistry
    • Cell Biology
    • Biochemistry, medical

    Cite this

    A comparison of plasma polymorphonuclear leucocyte elastase levels in obese and lean individuals. / Adeyemi, E.; Benedict, S.; Abdulle, Abdishakur.

    In: Journal of International Medical Research, Vol. 26, No. 5, 01.01.1998, p. 252-256.

    Research output: Contribution to journalArticle

    Adeyemi, E. ; Benedict, S. ; Abdulle, Abdishakur. / A comparison of plasma polymorphonuclear leucocyte elastase levels in obese and lean individuals. In: Journal of International Medical Research. 1998 ; Vol. 26, No. 5. pp. 252-256.
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