A biophysical model of cochlear processing

intensity dependence of pure tone responses.

S. A. Shamma, R. S. Chadwick, W. J. Wilbur, K. A. Morrish, J. Rinzel

Research output: Contribution to journalArticle

Abstract

A mathematical model of cochlear processing is developed to account for the nonlinear dependence of frequency selectivity on intensity in inner hair cell and auditory nerve fiber responses. The model describes the transformation from acoustic stimulus to intracellular hair cell potentials in the cochlea. It incorporates a linear formulation of basilar membrane mechanics and subtectorial fluid-cilia displacement coupling, and a simplified description of the inner hair cell nonlinear transduction process. The analysis at this stage is restricted to low-frequency single tones. The computed responses to single tone inputs exhibit the experimentally observed nonlinear effects of increasing intensity such as the increase in the bandwidth of frequency selectivity and the downward shift of the best frequency. In the model, the first effect is primarily due to the saturating effect of the hair cell nonlinearity. The second results from the combined effects of both the nonlinearity and of the inner hair cell low-pass transfer function. In contrast to these shifts along the frequency axis, the model does not exhibit intensity dependent shifts of the spatial location along the cochlea of the peak response for a given single tone. The observed shifts therefore do not contradict an intensity invariant tonotopic code.

Original languageEnglish (US)
Pages (from-to)133-145
Number of pages13
JournalJournal of the Acoustical Society of America
Volume80
Issue number1
StatePublished - Jul 1986

Fingerprint

hair
cochlea
shift
selectivity
nonlinearity
nerve fibers
transfer functions
stimuli
mathematical models
Cells
membranes
low frequencies
bandwidth
formulations
acoustics
fluids
Nonlinearity
Cochlea

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

A biophysical model of cochlear processing : intensity dependence of pure tone responses. / Shamma, S. A.; Chadwick, R. S.; Wilbur, W. J.; Morrish, K. A.; Rinzel, J.

In: Journal of the Acoustical Society of America, Vol. 80, No. 1, 07.1986, p. 133-145.

Research output: Contribution to journalArticle

Shamma, S. A. ; Chadwick, R. S. ; Wilbur, W. J. ; Morrish, K. A. ; Rinzel, J. / A biophysical model of cochlear processing : intensity dependence of pure tone responses. In: Journal of the Acoustical Society of America. 1986 ; Vol. 80, No. 1. pp. 133-145.
@article{ee86e4a46dd44fb3825af5a240b50ad3,
title = "A biophysical model of cochlear processing: intensity dependence of pure tone responses.",
abstract = "A mathematical model of cochlear processing is developed to account for the nonlinear dependence of frequency selectivity on intensity in inner hair cell and auditory nerve fiber responses. The model describes the transformation from acoustic stimulus to intracellular hair cell potentials in the cochlea. It incorporates a linear formulation of basilar membrane mechanics and subtectorial fluid-cilia displacement coupling, and a simplified description of the inner hair cell nonlinear transduction process. The analysis at this stage is restricted to low-frequency single tones. The computed responses to single tone inputs exhibit the experimentally observed nonlinear effects of increasing intensity such as the increase in the bandwidth of frequency selectivity and the downward shift of the best frequency. In the model, the first effect is primarily due to the saturating effect of the hair cell nonlinearity. The second results from the combined effects of both the nonlinearity and of the inner hair cell low-pass transfer function. In contrast to these shifts along the frequency axis, the model does not exhibit intensity dependent shifts of the spatial location along the cochlea of the peak response for a given single tone. The observed shifts therefore do not contradict an intensity invariant tonotopic code.",
author = "Shamma, {S. A.} and Chadwick, {R. S.} and Wilbur, {W. J.} and Morrish, {K. A.} and J. Rinzel",
year = "1986",
month = "7",
language = "English (US)",
volume = "80",
pages = "133--145",
journal = "Journal of the Acoustical Society of America",
issn = "0001-4966",
publisher = "Acoustical Society of America",
number = "1",

}

TY - JOUR

T1 - A biophysical model of cochlear processing

T2 - intensity dependence of pure tone responses.

AU - Shamma, S. A.

AU - Chadwick, R. S.

AU - Wilbur, W. J.

AU - Morrish, K. A.

AU - Rinzel, J.

PY - 1986/7

Y1 - 1986/7

N2 - A mathematical model of cochlear processing is developed to account for the nonlinear dependence of frequency selectivity on intensity in inner hair cell and auditory nerve fiber responses. The model describes the transformation from acoustic stimulus to intracellular hair cell potentials in the cochlea. It incorporates a linear formulation of basilar membrane mechanics and subtectorial fluid-cilia displacement coupling, and a simplified description of the inner hair cell nonlinear transduction process. The analysis at this stage is restricted to low-frequency single tones. The computed responses to single tone inputs exhibit the experimentally observed nonlinear effects of increasing intensity such as the increase in the bandwidth of frequency selectivity and the downward shift of the best frequency. In the model, the first effect is primarily due to the saturating effect of the hair cell nonlinearity. The second results from the combined effects of both the nonlinearity and of the inner hair cell low-pass transfer function. In contrast to these shifts along the frequency axis, the model does not exhibit intensity dependent shifts of the spatial location along the cochlea of the peak response for a given single tone. The observed shifts therefore do not contradict an intensity invariant tonotopic code.

AB - A mathematical model of cochlear processing is developed to account for the nonlinear dependence of frequency selectivity on intensity in inner hair cell and auditory nerve fiber responses. The model describes the transformation from acoustic stimulus to intracellular hair cell potentials in the cochlea. It incorporates a linear formulation of basilar membrane mechanics and subtectorial fluid-cilia displacement coupling, and a simplified description of the inner hair cell nonlinear transduction process. The analysis at this stage is restricted to low-frequency single tones. The computed responses to single tone inputs exhibit the experimentally observed nonlinear effects of increasing intensity such as the increase in the bandwidth of frequency selectivity and the downward shift of the best frequency. In the model, the first effect is primarily due to the saturating effect of the hair cell nonlinearity. The second results from the combined effects of both the nonlinearity and of the inner hair cell low-pass transfer function. In contrast to these shifts along the frequency axis, the model does not exhibit intensity dependent shifts of the spatial location along the cochlea of the peak response for a given single tone. The observed shifts therefore do not contradict an intensity invariant tonotopic code.

UR - http://www.scopus.com/inward/record.url?scp=0022741733&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022741733&partnerID=8YFLogxK

M3 - Article

VL - 80

SP - 133

EP - 145

JO - Journal of the Acoustical Society of America

JF - Journal of the Acoustical Society of America

SN - 0001-4966

IS - 1

ER -