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Yingkai Zhang

Professor of Chemistry

    1993 …2019
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    Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

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    Research Output 1993 2019

    • 90 Article
    • 2 Chapter (peer-reviewed)
    • 1 Chapter
    • 1 Comment/debate

    A Conserved Allosteric Pathway in Tyrosine Kinase Regulation

    Marsiglia, W. M., Katigbak, J., Zheng, S., Mohammadi, M., Zhang, Y. & Traaseth, N. J., Aug 6 2019, In : Structure. 27, 8, p. 1308-1315.e3

    Research output: Contribution to journalArticle

    Isoleucine
    Phenylalanine
    Protein-Tyrosine Kinases
    Phosphotransferases
    Mutation

    Identification and structure-function analyses of an allosteric inhibitor of the tyrosine phosphatase PTPN22

    Li, K., Hou, X., Li, R., Bi, W., Yang, F., Chen, X., Xiao, P., Liu, T., Lu, T., Zhou, Y., Tian, Z., Shen, Y., Zhang, Y., Wang, J., Fang, H., Sun, J. & Yu, X., Jan 1 2019, In : Journal of Biological Chemistry. 294, 21, p. 8653-8663 11 p.

    Research output: Contribution to journalArticle

    Protein Tyrosine Phosphatases
    Phosphatases
    Phosphoric Monoester Hydrolases
    Tyrosine
    Allosteric Site

    Intrinsic cleavage of RNA polymerase II adopts a nucleobase-independent mechanism assisted by transcript phosphate

    Tse, C. K. M., Xu, J., Xu, L., Sheong, F. K., Wang, S., Chow, H. Y., Gao, X., Li, X., Cheung, P. P. H., Wang, D., Zhang, Y. & Huang, X., Mar 1 2019, In : Nature Catalysis. 2, 3, p. 228-235 8 p.

    Research output: Contribution to journalArticle

    RNA Polymerase II
    RNA
    Phosphates
    Oxygen
    Mechanics
    field theory (physics)
    Tensors
    tensors
    Neural networks
    learning

    Two symmetric arginine residues play distinct roles in thermus thermophilus argonaute DNA guide strand-mediated DNA target cleavage

    Lei, J., Sheng, G., Cheung, P. P. H., Wang, S., Li, Y., Gao, X., Zhang, Y., Wang, Y. & Huang, X., Jan 15 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 3, p. 845-853 9 p.

    Research output: Contribution to journalArticle

    R 486
    Thermus thermophilus
    DNA Cleavage
    Arginine
    DNA