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Lara Mahal

Professor of Chemistry

19972019
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Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

Lectins Medicine & Life Sciences
Polysaccharides Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Glycomics Medicine & Life Sciences
Microarrays Chemical Compounds
Carbohydrates Medicine & Life Sciences
Technology Medicine & Life Sciences
Microarray Analysis Medicine & Life Sciences

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Research Output 1997 2019

O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

Bandini, G., Leon, D. R., Hoppe, C. M., Zhang, Y., Agop-Nersesian, C., Shears, M. J., Mahal, L., Routier, F. H., Costello, C. E. & Samuelson, J., Jan 1 2019, In : Journal of Biological Chemistry. 294, 6, p. 1967-1983 17 p.

Research output: Contribution to journalArticle

Thrombospondins
Toxoplasma
Processing
Proteins
Disaccharides

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

Gaschler, M. M., Andia, A. A., Liu, H., Csuka, J. M., Hurlocker, B., Vaiana, C. A., Heindel, D. W., Zuckerman, D. S., Bos, P. H., Reznik, E., Ye, L. F., Tyurina, Y. Y., Lin, A. J., Shchepinov, M. S., Chan, A. Y., Peguero-Pereira, E., Fomich, M. A., Daniels, J. D., Bekish, A. V., Shmanai, V. V. & 4 others, Kagan, V. E., Mahal, L., Woerpel, K. & Stockwell, B. R., May 1 2018, In : Nature Chemical Biology. 14, 5, p. 507-515 9 p.

Research output: Contribution to journalArticle

Lipid Peroxides
Hydroxyl Radical
Lipid Peroxidation
Glutathione
Cell Death

Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility

Koppolu, S., Wang, L., Mathur, A., Nigam, J. A., Dezzutti, C. S., Isaacs, C., Meyn, L., Bunge, K. E., Moncla, B. J., Hillier, S. L., Rohan, L. C. & Mahal, L., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Mannose
Antiviral Agents
Innate Immunity
Drug Compounding
Therapeutic Irrigation

XBP1s activation can globally remodel N-glycan structure distribution patterns

Wong, M. Y., Chen, K., Antonopoulos, A., Kasperc, B. T., Dewal, M. B., Taylor, R. J., Whittaker, C. A., Hein, P. P., Dell, A., Genereux, J. C., Haslam, S. M., Mahal, L. & Shoulders, M. D., Oct 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10089-E10098

Research output: Contribution to journalArticle

Polysaccharides
Unfolded Protein Response
Secretory Pathway
Proteome
X-Box Binding Protein 1

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

Agrawal, P., Fontanals-Cirera, B., Sokolova, E., Jacob, S., Vaiana, C. A., Argibay, D., Davalos, V., McDermott, M., Nayak, S., Darvishian, F., Castillo, M., Ueberheide, B., Osman, I., Fenyö, D., Mahal, L. & Hernando, E., Jun 12 2017, In : Cancer Cell. 31, 6, p. 804-819.e7

Research output: Contribution to journalArticle

Systems Biology
Melanoma
Neural Cell Adhesion Molecule L1
Neoplasm Metastasis
Glycomics