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Lara Mahal

Professor of Chemistry

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    Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

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    Research Output 1997 2019

    O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

    Bandini, G., Leon, D. R., Hoppe, C. M., Zhang, Y., Agop-Nersesian, C., Shears, M. J., Mahal, L., Routier, F. H., Costello, C. E. & Samuelson, J., Jan 1 2019, In : Journal of Biological Chemistry. 294, 6, p. 1967-1983 17 p.

    Research output: Contribution to journalArticle


    FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

    Gaschler, M. M., Andia, A. A., Liu, H., Csuka, J. M., Hurlocker, B., Vaiana, C. A., Heindel, D. W., Zuckerman, D. S., Bos, P. H., Reznik, E., Ye, L. F., Tyurina, Y. Y., Lin, A. J., Shchepinov, M. S., Chan, A. Y., Peguero-Pereira, E., Fomich, M. A., Daniels, J. D., Bekish, A. V., Shmanai, V. V. & 4 others, Kagan, V. E., Mahal, L., Woerpel, K. & Stockwell, B. R., May 1 2018, In : Nature Chemical Biology. 14, 5, p. 507-515 9 p.

    Research output: Contribution to journalArticle

    Lipid Peroxides
    Hydroxyl Radical
    Lipid Peroxidation
    Cell Death

    Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility

    Koppolu, S., Wang, L., Mathur, A., Nigam, J. A., Dezzutti, C. S., Isaacs, C., Meyn, L., Bunge, K. E., Moncla, B. J., Hillier, S. L., Rohan, L. C. & Mahal, L., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

    Research output: Contribution to journalArticle

    Antiviral Agents
    Innate Immunity
    Drug Compounding
    Therapeutic Irrigation

    XBP1s activation can globally remodel N-glycan structure distribution patterns

    Wong, M. Y., Chen, K., Antonopoulos, A., Kasperc, B. T., Dewal, M. B., Taylor, R. J., Whittaker, C. A., Hein, P. P., Dell, A., Genereux, J. C., Haslam, S. M., Mahal, L. & Shoulders, M. D., Oct 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10089-E10098

    Research output: Contribution to journalArticle

    Unfolded Protein Response
    Secretory Pathway
    X-Box Binding Protein 1

    A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

    Agrawal, P., Fontanals-Cirera, B., Sokolova, E., Jacob, S., Vaiana, C. A., Argibay, D., Davalos, V., McDermott, M., Nayak, S., Darvishian, F., Castillo, M., Ueberheide, B., Osman, I., Fenyö, D., Mahal, L. & Hernando, E., Jun 12 2017, In : Cancer Cell. 31, 6, p. 804-819.e7

    Research output: Contribution to journalArticle

    Systems Biology
    Neural Cell Adhesion Molecule L1
    Neoplasm Metastasis