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David Scicchitano

Professor Of Biology, Dean of Science

1982 …2018
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Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

  • 2 Similar Profiles
DNA Repair Medicine & Life Sciences
DNA Medicine & Life Sciences
Transcription Chemical Compounds
DNA Adducts Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Repair Chemical Compounds
Alkyl and Aryl Transferases Medicine & Life Sciences
Epoxy Compounds Medicine & Life Sciences

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Research Output 1982 2018

Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair

Burns, J. A., Chowdhury, M. A., Cartularo, L., Berens, C. & Scicchitano, D., Apr 20 2018, In : Nucleic acids research. 46, 7, p. 3498-3516 19 p.

Research output: Contribution to journalArticle

Open Access
DNA Repair
Microsatellite Repeats
Base Pairing
Trinucleotide Repeat Expansion

O6-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

Ezerskyte, M., Paredes, J. A., Malvezzi, S., Burns, J. A., Margison, G. P., Olsson, M., Scicchitano, D. A. & Dreij, K., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4731-4736 6 p.

Research output: Contribution to journalArticle

Alkyl and Aryl Transferases
G1 Phase Cell Cycle Checkpoints

The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro

Kolbanovskiy, M., Chowdhury, M. A., Nadkarni, A., Broyde, S., Geacintov, N. E., Scicchitano, D. A. & Shafirovich, V., Jun 20 2017, In : Biochemistry. 56, 24, p. 3008-3018 11 p.

Research output: Contribution to journalArticle

RNA Polymerase II
DNA Repair

Nucleotide excision repair and transcription-coupled DNA repair abrogate the impact of DNA damage on transcription

Nadkarni, A., Burns, J. A., Gandolfi, A., Chowdhury, M. A., Cartularo, L., Berens, C., Geacintov, N. & Scicchitano, D., Jan 8 2016, In : Journal of Biological Chemistry. 291, 2, p. 848-861 14 p.

Research output: Contribution to journalArticle

DNA Repair
DNA Damage
JNK Mitogen-Activated Protein Kinases
Epoxy Compounds