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David Scicchitano

Professor Of Biology, Dean of Science

    1982 …2018
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    Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

    • 3 Similar Profiles
    DNA Repair Medicine & Life Sciences
    DNA Medicine & Life Sciences
    Transcription Chemical Compounds
    DNA Adducts Medicine & Life Sciences
    RNA Polymerase II Medicine & Life Sciences
    Repair Chemical Compounds
    Alkyl and Aryl Transferases Medicine & Life Sciences
    Epoxy Compounds Medicine & Life Sciences

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    Research Output 1982 2018

    Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair

    Burns, J. A., Chowdhury, M. A., Cartularo, L., Berens, C. & Scicchitano, D., Apr 20 2018, In : Nucleic acids research. 46, 7, p. 3498-3516 19 p.

    Research output: Contribution to journalArticle

    Open Access
    DNA Repair
    Microsatellite Repeats
    Base Pairing
    Trinucleotide Repeat Expansion

    O6-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

    Ezerskyte, M., Paredes, J. A., Malvezzi, S., Burns, J. A., Margison, G. P., Olsson, M., Scicchitano, D. A. & Dreij, K., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4731-4736 6 p.

    Research output: Contribution to journalArticle

    Alkyl and Aryl Transferases
    G1 Phase Cell Cycle Checkpoints

    The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro

    Kolbanovskiy, M., Chowdhury, M. A., Nadkarni, A., Broyde, S., Geacintov, N. E., Scicchitano, D. A. & Shafirovich, V., Jun 20 2017, In : Biochemistry. 56, 24, p. 3008-3018 11 p.

    Research output: Contribution to journalArticle

    RNA Polymerase II
    DNA Repair

    Nucleotide excision repair and transcription-coupled DNA repair abrogate the impact of DNA damage on transcription

    Nadkarni, A., Burns, J. A., Gandolfi, A., Chowdhury, M. A., Cartularo, L., Berens, C., Geacintov, N. & Scicchitano, D., Jan 8 2016, In : Journal of Biological Chemistry. 291, 2, p. 848-861 14 p.

    Research output: Contribution to journalArticle

    DNA Repair
    DNA Damage
    JNK Mitogen-Activated Protein Kinases
    Epoxy Compounds