David Scicchitano

Professor Of Biology, Dean of Science

1982 …2018
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where David Scicchitano is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
DNA Repair Medicine & Life Sciences
DNA Medicine & Life Sciences
DNA Adducts Medicine & Life Sciences
Transcription Chemical Compounds
RNA Polymerase II Medicine & Life Sciences
Repair Chemical Compounds
Alkyl and Aryl Transferases Medicine & Life Sciences
Epoxy Compounds Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1982 2018

Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair

Burns, J. A., Chowdhury, M. A., Cartularo, L., Berens, C. & Scicchitano, D., Apr 20 2018, In : Nucleic acids research. 46, 7, p. 3498-3516 19 p.

Research output: Contribution to journalArticle

Open Access
DNA Repair
Microsatellite Repeats
DNA
Base Pairing
Trinucleotide Repeat Expansion

O6-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

Ezerskyte, M., Paredes, J. A., Malvezzi, S., Burns, J. A., Margison, G. P., Olsson, M., Scicchitano, D. A. & Dreij, K., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4731-4736 6 p.

Research output: Contribution to journalArticle

Mutagenesis
Neoplasms
Carcinogenesis
Alkyl and Aryl Transferases
G1 Phase Cell Cycle Checkpoints

The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro

Kolbanovskiy, M., Chowdhury, M. A., Nadkarni, A., Broyde, S., Geacintov, N. E., Scicchitano, D. A. & Shafirovich, V., Jun 20 2017, In : Biochemistry. 56, 24, p. 3008-3018 11 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Elongation
DNA Repair
Transcription
DNA

Nucleotide excision repair and transcription-coupled DNA repair abrogate the impact of DNA damage on transcription

Nadkarni, A., Burns, J. A., Gandolfi, A., Chowdhury, M. A., Cartularo, L., Berens, C., Geacintov, N. & Scicchitano, D., Jan 8 2016, In : Journal of Biological Chemistry. 291, 2, p. 848-861 14 p.

Research output: Contribution to journalArticle

Transcription
DNA Repair
DNA Damage
Repair
Nucleotides
JNK Mitogen-Activated Protein Kinases
Benzo(a)pyrene
Epoxy Compounds
Fibroblasts
Interleukins