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Andrew Hamilton


1977 …2019
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Fingerprint Weighted list of dominant concepts in the researcher's publications (titles and abstracts).

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Farnesyltranstransferase Medicine & Life Sciences
Artificial Receptors Chemical Compounds
Scaffolds Chemical Compounds
Hydrogen bonds Chemical Compounds
Prenylation Medicine & Life Sciences
Peptidomimetics Medicine & Life Sciences
Molecular recognition Chemical Compounds
Proteins Chemical Compounds

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Research Output 1977 2019

Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors

Kazi, A., Xiang, S., Yang, H., Chen, L., Kennedy, P., Ayaz, M., Fletcher, S., Cummings, C., Lawrence, H. R., Beato, F., Kang, Y., Kim, M. P., Delitto, A., Underwood, P. W., Fleming, J. B., Trevino, J. G., Hamilton, A. & Sebti, S. M., Oct 1 2019, In : Clinical Cancer Research. 25, 19, p. 5984-5996 13 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms

Heterofunctionalized Cavitands by Macrocyclization of Sequence-Defined Foldamers

Meisel, J. W., Hu, C. T. & Hamilton, A., Oct 4 2019, In : Organic Letters. 21, 19, p. 7763-7767 5 p.

Research output: Contribution to journalArticle

Open Access
Functional groups
Bearings (structural)
Artificial Receptors
Molecular recognition
Solid-Phase Synthesis Techniques

α-Helix-Mimetic Foldamers for Targeting HIV-1 TAR RNA

Maity, D., Kumar, S., Curreli, F., Debnath, A. K. & Hamilton, A., Jan 1 2019, In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

Scaffolds (biology)

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

Lee, C. H., Yu, J. R., Kumar, S., Jin, Y., LeRoy, G., Bhanu, N., Kaneko, S., Garcia, B. A., Hamilton, A. & Reinberg, D., Jan 1 2018, (Accepted/In press) In : Molecular Cell.

Research output: Contribution to journalArticle

Personnel Selection
Clinical Trials

Mimicry of a β-Hairpin Turn by a Nonpeptidic Laterally Flexible Foldamer

Meisel, J. W., Hu, C. T. & Hamilton, A., Jul 6 2018, In : Organic Letters. 20, 13, p. 3879-3882 4 p.

Research output: Contribution to journalArticle

Hydrogen bonds