Basic Science and Craniofacial Biology

Research Output 1967 2019

2019

Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride

Li, Y., Liu, Y., Psoter, W. J., Nguyen, O. M., Bromage, T., Walters, M., Hu, B., Rabieh, S. & Kumararaja, F. C., Jan 1 2019, In : Caries Research.

Research output: Contribution to journalArticle

Deciduous Tooth
Silver
X-Ray Emission Spectrometry
Dental Enamel
Electron Scanning Microscopy

ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

Neginskaya, M. A., Solesio, M. E., Berezhnaya, E. V., Amodeo, G. F., Mnatsakanyan, N., Jonas, E. A. & Pavlov, E., Jan 2 2019, In : Cell Reports. 26, 1, p. 11-17.e2

Research output: Contribution to journalArticle

Mitochondria
Cyclosporine
Permeability
Adenosine Triphosphate
Bongkrekic Acid

Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model

Wang, S., Wang, N., Yu, B., Cao, M., Wang, Y., Guo, Y., Zhang, Y., Zhang, P., Yu, X., Wang, S., Zeng, L., Liang, B., Li, X. & Wu, Y., Sep 5 2019, In : Oncogene. 38, 36, p. 6338-6353 16 p.

Research output: Contribution to journalArticle

Somatomedins
Transgenic Mice
Prostate
Adenocarcinoma
Prostatic Neoplasms

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody

He, S., Fu, Y., Guo, J., Spear, M., Yang, J., Trinité, B., Qin, C., Fu, S., Jiang, Y., Zhang, Z., Xu, J., Ding, H., Levy, D., Chen, W., Petricoin, E., Liotta, L. A., Shang, H. & Wu, Y., Jan 1 2019, In : Virginia Law Review. 104, 8, eaat7911.

Research output: Contribution to journalArticle

migration
helper

Comparative Effect of Two Red Lights on Streptococcus mutans Biofilms and Assessment of Temperature Variances in Human Teeth During In Vitro Photodynamic Antimicrobial Chemotherapy

Aragão, M. G. B., Costa, C. A. G. D. A., Lima, R. A., Rodrigues, L. K. A., Duarte, S. & Zanin, I. C. J., Jan 1 2019, In : Photobiomodulation, photomedicine, and laser surgery. 37, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Open Access
Streptococcus mutans
Chemotherapy
Biofilms
Tooth
Light
Open Access
Biomineralization
Minerals
Nanoparticles
Proteins
Calcium Carbonate

Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease

Babitt, J. L. & Sitara, D., Jul 1 2019, In : Current opinion in nephrology and hypertension. 28, 4, p. 304-310 7 p.

Research output: Contribution to journalArticle

Kidney Diseases
Erythropoietin
Iron
Inflammation
Chronic Renal Insufficiency

Daily phototherapy with red light to regulate candida albicans biofilm growth

Panariello, B. H. D., Garcia, B. A. & Duarte, S., Apr 1 2019, In : Journal of Visualized Experiments. 2019, 146, e59326.

Research output: Contribution to journalArticle

Phototherapy
Candida
Biofilms
Candida albicans
Light

Developmental biology of the meninges

Dasgupta, K. & Jeong, J., Jan 1 2019, In : Genesis. e23288.

Research output: Contribution to journalReview article

Developmental Biology
Meninges
Skull
Brain
Pia Mater

Differential regulation of Ca 2+ influx by Orai channels mediates enamel mineralization

Eckstein, M., Vaeth, M., Aulestia, F. J., Costiniti, V., Kassam, S. N., Bromage, T., Pedersen, P., Issekutz, T., Idaghdhour, Y., Moursi, A., Feske, S. & Lacruz, R., Jan 1 2019, In : Science Signaling. 12, 578, aav4663.

Research output: Contribution to journalArticle

Enamels
Dental Enamel
Endoplasmic Reticulum
Defects
Oxidation-Reduction

Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation

Seidlmayer, L. K., Gomez-Garcia, M. R., Shiba, T., Porter, G. A., Pavlov, E., Bers, D. M. & Dedkova, E. N., Feb 15 2019, In : Archives of Biochemistry and Biophysics. 662, p. 177-189 13 p.

Research output: Contribution to journalArticle

Polyphosphates
Chain length
Cardiac Myocytes
Energy Metabolism
Chemical activation
Open Access
Aryl Hydrocarbon Receptors
Cytochrome P-450 CYP1A1
Aerosols
Tobacco Products
Carcinogens

Effects of the Tobacco Carcinogens N'-Nitrosonornicotine and Dibenzo[a,l]pyrene Individually and in Combination on DNA Damage in Human Oral Leukoplakia and on Mutagenicity and Mutation Profiles in lacI Mouse Tongue

Guttenplan, J., Chen, K. M., Sun, Y. W., Shalaby, N. A. E., Kosinska, W., Desai, D., Gowda, K., Amin, S. & El-Bayoumy, K., Sep 16 2019, In : Chemical research in toxicology. 32, 9, p. 1893-1899 7 p.

Research output: Contribution to journalArticle

N'-nitrosonornicotine
Oral Leukoplakia
Tobacco
Tongue
Carcinogens

Identification of ZYG11A as a candidate IGF1-dependent protooncogene in endometrial cancer

Achlaug, L., Sarfstein, R., Nagaraj, K., Lapkina-Gendler, L., Bruchim, I., Dixit, M., Laron, Z., Yakar, S. & Werner, H., Jul 1 2019, In : Oncotarget. 10, 43, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

Laron Syndrome
Endometrial Neoplasms
Neoplasms
Carcinoma
Somatotropin Receptors

Inhibition of Karyopherin beta 1 suppresses prostate cancer growth

Yang, J., Guo, Y., Lu, C., Zhang, R., Wang, Y., Luo, L., Zhang, Y., Chu, C. H., Wang, K. J., Obbad, S., Yan, W. & Li, X., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

beta Karyopherins
Prostatic Neoplasms
Growth
Cell Cycle
Karyopherins

Innate αβ T cells mediate antitumor immunity by orchestrating immunogenic macrophage programming

Hundeyin, M., Kurz, E., Mishra, A., Rossi, J. A. K., Liudahl, S. M., Leis, K. R., Mehrotra, H., Kim, M., Torres, L. E., Ogunsakin, A., Link, J., Sears, R. C., Sivagnanam, S., Goecks, J., Islam, K. M. S., Dolgalev, I., Savadkar, S., Wang, W., Aykut, B., Leinwand, J. & 17 others, Diskin, B., Adam, S., Israr, M., Gelas, M., Lish, J., Chin, K., Farooq, M. S., Wadowski, B., Wu, J., Shah, S., Adeegbe, D. O., Pushalkar, S., Vasudevaraja, V., Saxena, D., Wong, K. K., Coussens, L. M. & Miller, G., Jan 1 2019, In : Cancer Discovery. 9, 9, p. 1288-1305 18 p.

Research output: Contribution to journalArticle

Open Access
Immunity
Macrophages
T-Lymphocytes
Adenocarcinoma
Neoplasms

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

Ran, L., Wang, X., Mi, A., Liu, Y., Wu, J., Wang, H., Guo, M., Sun, J., Liu, B., Li, Y., Wang, D., Jiang, R., Wang, N., Gao, W., Zeng, L., Huang, L., Chen, X., LeRoith, D., Liang, B., Li, X. & 1 others, Wu, Y., Jun 28 2019, In : iScience. 16, p. 106-121 16 p.

Research output: Contribution to journalArticle

Open Access
Somatotropin Receptors
Brown Adipose Tissue
Thermogenesis
Fatty Acids
Endocrinology

Low IGF-I Bioavailability Impairs Growth and Glucose Metabolism in a Mouse Model of Human PAPPA2 p.Ala1033Val Mutation

Fujimoto, M., Andrew, M., Liao, L., Zhang, D., Yildirim, G., Sluss, P., Kalra, B., Kumar, A., Yakar, S., Hwa, V. & Dauber, A., Jun 1 2019, In : Endocrinology. 160, 6, p. 1363-1376 14 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
Biological Availability
Glucose
Mutation
Growth

Low-temperature plasma on peri-implant-related biofilm and gingival tissue

Carreiro, A. F. P., Delben, J. A., Guedes, S., Silveira, E. J. D., Janal, M. N., Vergani, C. E., Pushalkar, S. & Duarte, S., May 1 2019, In : Journal of periodontology. 90, 5, p. 507-515 9 p.

Research output: Contribution to journalArticle

Biofilms
Temperature
Epithelium
Vascular Endothelial Growth Factor A
Porphyromonas gingivalis

Mammalian Taste Cells Express Functional Olfactory Receptors

Malik, B., Elkaddi, N., Turkistani, J., Spielman, A. & Ozdener, M. H., May 29 2019, In : Chemical senses. 44, 5, p. 289-301 13 p.

Research output: Contribution to journalArticle

Odorant Receptors
Adenylyl Cyclases
Form Perception
Green Fluorescent Proteins
Tongue

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

Dasgupta, K., Chung, J. U., Asam, K. & Jeong, J., Nov 15 2019, In : Developmental Biology. 455, 2, p. 434-448 15 p.

Research output: Contribution to journalArticle

Mesoderm
Genome
Skull
Meninges
Head

NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal

Trinité, B., Zhang, H. & Levy, D., Jun 26 2019, In : Retrovirology. 16, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
HIV-1
T-Lymphocytes
efavirenz
Infection
Convulsive Therapy

Non-thermal plasma treatment to enhance the adhesion between enamel surface and orthodontic bracket

Almoammar, S., Alshahrani, I., Asiry, M. A., Duarte, S., Janal, M. & Khoo, E., Jan 1 2019, In : Bio-Medical Materials and Engineering. 30, 4, p. 439-448 10 p.

Research output: Contribution to journalArticle

Enamels
Bond strength (materials)
Adhesion
Thermal cycling
Plasmas

Novel Nicotine Delivery Systems

Kumar, P. S., Clark, P., Brinkman, M. C. & Saxena, D., Oct 1 2019, In : Advances in dental research. 30, 1, p. 11-15 5 p.

Research output: Contribution to journalReview article

Microbiology
Nicotine
DNA Sequence Analysis
Tobacco Products
Bacteria

Parathyroid hormone-stimulation of Runx2 during osteoblast differentiation via the regulation of lnc-SUPT3H-1:16 (RUNX2-AS1:32) and miR-6797-5p

Arumugam, B., Vishal, M., Shreya, S., Malavika, D., Rajpriya, V., He, Z., Partridge, N. & Selvamurugan, N., Mar 1 2019, In : Biochimie. 158, p. 43-52 10 p.

Research output: Contribution to journalArticle

Osteoblasts
Parathyroid Hormone
Long Noncoding RNA
Bone
Mesenchymal Stromal Cells

Periodontal disease in a young Romanian convenience sample: Radiographic assessment

Hategan, S. I., Kamer, A., Sinescu, C., Craig, R., Jivanescu, A., Gavrilovici, A. M. & Negrutiu, M. L., May 29 2019, In : BMC Oral Health. 19, 1, 94.

Research output: Contribution to journalArticle

Open Access
Periodontal Diseases
Mouth Rehabilitation
Prosthodontics
Tooth
Aggressive Periodontitis

Positioning a multifunctional basic helix-loop-helix transcription factor within the Ciona notochord gene regulatory network

Kugler, J. E., Wu, Y., Katikala, L., Passamaneck, Y. J., Addy, J., Caballero, N., Oda-Ishii, I., Maguire, J. E., Li, R. & Di Gregorio, A., Jan 1 2019, (Accepted/In press) In : Developmental Biology.

Research output: Contribution to journalArticle

Basic Helix-Loop-Helix Transcription Factors
Notochord
Gene Regulatory Networks
Mesoderm
Nervous System
Open Access
skeletal development
Sea Urchins
Echinoidea
Agglomeration
Proteins

Sophorolipid Biosurfactants Activate Taste Receptor Type 1 Member 3-Mediated Taste Responses and Block Responses to Bitter Taste In Vitro and In Vivo

Ozdener, M. H., Ashby, R. D., Jyotaki, M., Elkaddi, N., Spielman, A., Bachmanov, A. A. & Solaiman, D. K. Y., Jan 1 2019, In : Journal of Surfactants and Detergents.

Research output: Contribution to journalArticle

taste
Candida
Palmitic acid
Laundries
Stearic acid

Targeting cellular metabolism to reduce head and neck cancer growth

Yang, J., Guo, Y., Seo, W., Zhang, R., Lu, C., Wang, Y., Luo, L., Paul, B., Yan, W., Saxena, D. & Li, X., Dec 1 2019, In : Scientific Reports. 9, 1, 4995.

Research output: Contribution to journalArticle

Open Access
Glutaminase
Head and Neck Neoplasms
Metformin
Growth
Glutamine

The Biomineralization Proteome: Protein Complexity for a Complex Bioceramic Assembly Process

Evans, J., Jan 1 2019, In : Proteomics. 19, 16, 1900036.

Research output: Contribution to journalReview article

Biomineralization
Bioceramics
Mollusca
Proteome
Minerals

The evolutionary history of the human face

Lacruz, R., Stringer, C. B., Kimbel, W. H., Wood, B., Harvati, K., O’Higgins, P., Bromage, T. & Arsuaga, J. L., May 1 2019, In : Nature Ecology and Evolution. 3, 5, p. 726-736 11 p.

Research output: Contribution to journalReview article

skeleton
bone
fossil
history
analysis

The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL

Aykut, B., Pushalkar, S., Chen, R., Li, Q., Abengozar, R., Kim, J. I., Shadaloey, S. A., Wu, D., Preiss, P., Verma, N., Guo, Y., Saxena, A., Vardhan, M., Diskin, B., Wang, W., Leinwand, J., Kurz, E., Kochen Rossi, J. A., Hundeyin, M., Zambrinis, C. & 3 others, Li, X., Saxena, D. & Miller, G., Oct 10 2019, In : Nature. 574, 7777, p. 264-267 4 p.

Research output: Contribution to journalArticle

Mannose-Binding Lectin
Carcinogenesis
Adenocarcinoma
Neoplasms
Malassezia

The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy

Sethi, V., Vitiello, G. A., Saxena, D., Miller, G. & Dudeja, V., May 1 2019, In : Gastroenterology. 156, 7, p. 2097-2115.e2

Research output: Contribution to journalArticle

Microbiota
Pancreatic Neoplasms
Immunotherapy
Carcinogenesis
Neoplasms

The Teaching of Personalized Dentistry in North American Dental Schools: Changes from 2014 to 2017

Zheng, L. Y., Rifkin, B. R., Spielman, A., London, L. & London, S. D., Sep 1 2019, In : Journal of dental education. 83, 9, p. 1065-1075 11 p.

Research output: Contribution to journalArticle

Dental Schools
dentistry
Dentistry
Curriculum
Teaching

Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA

Douglas, J. E., Lin, C., Mansfield, C. J., Arayata, C. J., Cowart, B. J., Spielman, A., Adappa, N. D., Palmer, J. N., Cohen, N. A. & Reed, D. R., Jan 1 2019, In : Chemical Senses. 44, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

Messenger RNA
Heterozygote
Small Intestine
Genotype
Paranasal Sinuses

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

Vaeth, M., Wang, Y. H., Eckstein, M., Yang, J., Silverman, G. J., Lacruz, R., Kannan, K. & Feske, S., Dec 1 2019, In : Nature Communications. 10, 1, 1183.

Research output: Contribution to journalArticle

Open Access
Regulatory T-Lymphocytes
Cell Differentiation
Tissue
cells
effectors

Trans,trans-farnesol, an antimicrobial natural compound, improves glass ionomer cement properties

De Castilho, A. R. F., Rosalen, P. L., De Souza Araújo, I. J., Kitagawa, I. L., De Araújo Costa, C. A. G., Janal, M. N., Alves, M. C., Duarte, S., Filho, P. N. L., Stipp, R. N. & Puppin-Rontani, R. M., Jan 1 2019, In : PloS one. 14, 8, e0220718.

Research output: Contribution to journalArticle

Open Access
Farnesol
farnesol
Glass Ionomer Cements
cement
glass

Tunicates: From humble sea squirt to proud model organism

Irvine, S. Q., Ristoratore, F. & Di Gregorio, A., Jan 1 2019, In : Developmental Biology.

Research output: Contribution to journalEditorial

Urochordata
Oceans and Seas

Virome and bacteriome: two sides of the same coin

Stern, J., Miller, G., Li, X. & Saxena, D., Aug 1 2019, In : Current Opinion in Virology. 37, p. 37-43 7 p.

Research output: Contribution to journalReview article

HIV
Papillomaviridae
Viruses
Highly Active Antiretroviral Therapy
Carcinogenesis
2018

40 years of IGF1: Insulin-like growth factors: Actions on the skeleton

Yakar, S., Werner, H. & Rosen, C. J., Jul 1 2018, In : Journal of Molecular Endocrinology. 61, 1, p. T115-T137

Research output: Contribution to journalReview article

Somatomedins
Skeleton
Growth Hormone
Research Personnel
Osteocytes

Altered Ca2+ signaling in enamelopathies

Eckstein, M., Aulestia, F. J., Nurbaeva, M. K. & Lacruz, R., Jan 1 2018, (Accepted/In press) In : Biochimica et Biophysica Acta - Molecular Cell Research.

Research output: Contribution to journalArticle

Dental Enamel
Ameloblasts
Mastication
Ion Transport
Hardness

Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus

Bae, C. J., Hong, C. S. & Saint-Jeannet, J-P., Jan 15 2018, In : Biochemical and Biophysical Research Communications. 495, 3, p. 2257-2263 7 p.

Research output: Contribution to journalArticle

Neural Crest
Xenopus
Transcription Factors
Kallmann Syndrome
Extracellular Matrix Proteins

Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria

Cesario, J. M., Landin Malt, A., Chung, J. U., Khairallah, M. P., Dasgupta, K., Asam, K., Deacon, L. J., Choi, V., Almaidhan, A. A., Darwiche, N. A., Kim, J., Johnson, R. L. & Jeong, J., Jan 1 2018, (Accepted/In press) In : Developmental Biology.

Research output: Contribution to journalArticle

Mesoderm
Skull
Transcription Factors
Head
Sutures

A screening method for gastric cancer by oral microbiome detection

Sun, J. H., Li, X. L., Yin, J., Li, Y., Hou, B. X. & Zhang, Z., May 1 2018, In : Oncology Reports. 39, 5, p. 2217-2224 8 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Microbiota
Stomach Neoplasms
Population
Saliva

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity

Solesio, M. E., Peixoto, P. M., Debure, L., Madamba, S. M., de Leon, M. J., Wisniewski, T., Pavlov, E. & Fossati, S., Aug 1 2018, In : Aging Cell. 17, 4, e12787.

Research output: Contribution to journalArticle

Methazolamide
Carbonic Anhydrases
Amyloid
Acetazolamide
Carbonic Anhydrase Inhibitors

Caries outcome following an intensive fluoride varnish treatment regimen for children at high risk for early childhood caries

Paek, A. E., Li, Y., Wang, Z., So, P., Janal, M. N., Herman, N. G., Hopkins, A. & Chinn, C., Jan 1 2018, (Accepted/In press) In : International Journal of Paediatric Dentistry.

Research output: Contribution to journalArticle

Topical Fluorides
Streptococcus mutans
Tooth
Therapeutics
Recurrence

Characterization of Pax3 and Sox10 transgenic Xenopus laevis embryos as tools to study neural crest development

Alkobtawi, M., Ray, H., Barriga, E. H., Moreno, M., Kerney, R., Monsoro-Burq, A. H., Saint-Jeannet, J-P. & Mayor, R., Jan 1 2018, (Accepted/In press) In : Developmental Biology.

Research output: Contribution to journalArticle

Neural Crest
Xenopus laevis
Embryonic Structures
Genetically Modified Animals
Amphibians

CRAC channels in dental enamel cells

Eckstein, M. & Lacruz, R., Nov 1 2018, In : Cell Calcium. 75, p. 14-20 7 p.

Research output: Contribution to journalReview article

Dental Enamel
Tooth
Amelogenesis Imperfecta
Dental Enamel Hypoplasia
Channelopathies

Detection of Zika virus using reverse-transcription LAMP coupled with reverse dot blot analysis in saliva

Sabalza, M., Yasmin, R., Barber, C. A., Castro, T., Malamud, D., Kim, B. J., Zhu, H., Montagna, R. A. & Abrams, W. R., Feb 1 2018, In : PLoS One. 13, 2, e0192398.

Research output: Contribution to journalArticle

Zika virus
Transcription
saliva
Viruses
Saliva