Basic Science and Craniofacial Biology

Research Output

2020

Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species-mediated mitochondrial injury

Castro, C. M., Corciulo, C., Solesio, M. E., Liang, F., Pavlov, E. V. & Cronstein, B. N., Jan 1 2020, (Accepted/In press) In : FASEB Journal.

Research output: Contribution to journalArticle

Open Access

Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents

Urso, A., D'Ovidio, F., Xu, D., Emala, C. W., Bunnett, N. W. & Perez-Zoghbi, J. F., Feb 1 2020, In : American journal of physiology. Lung cellular and molecular physiology. 318, 2, p. L264-L275

Research output: Contribution to journalArticle

Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells

Aulestia, F. J., Groeling, J., Bomfim, G. H. S., Costiniti, V., Manikandan, V., Chaloemtoem, A., Concepcion, A. R., Li, Y., Wagner, L. E., Idaghdour, Y., Yule, D. I. & Lacruz, R. S., Feb 18 2020, In : Science signaling. 13, 619

Research output: Contribution to journalArticle

Inorganic polyphosphate is required for sustained free mitochondrial calcium elevation, following calcium uptake

Solesio, M. E., Garcia del Molino, L. C., Elustondo, P. A., Diao, C., Chang, J. C. & Pavlov, E. V., Mar 2020, In : Cell Calcium. 86, 102127.

Research output: Contribution to journalArticle

miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts

Malavkia, D., Shreya, S., Raj Priya, V., Rohini, M., He, Z., Partridge, N. C. & Selvamurugan, N., Jan 1 2020, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Morphological association between the muscles and bones in the craniofacial region

Yamamoto, M., Takada, H., Ishizuka, S., Kitamura, K., Jeong, J., Sato, M., Hinata, N. & Abe, S., Jan 1 2020, In : PloS one. 15, 1, e0227301.

Research output: Contribution to journalArticle

Open Access
Open Access

STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone

Gamage, T. H., Lengle, E., Gunnes, G., Pullisaar, H., Holmgren, A., Reseland, J. E., Merckoll, E., Corti, S., Mizobuchi, M., Morales, R. J., Tsiokas, L., Tjønnfjord, G. E., Lacruz, R. S., Lyngstadaas, S. P., Misceo, D. & Frengen, E., Jan 2020, In : Cell Calcium. 85, 102110.

Research output: Contribution to journalArticle

Open Access

The notochord gene regulatory network in chordate evolution: Conservation and divergence from Ciona to vertebrates

Di Gregorio, A., Jan 1 2020, (Accepted/In press) Current Topics in Developmental Biology. Academic Press Inc., (Current Topics in Developmental Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

TRPM7 activation potentiates SOCE in enamel cells but requires ORAI

Souza Bomfim, G. H., Costiniti, V., Li, Y., Idaghdour, Y. & Lacruz, R. S., May 2020, In : Cell Calcium. 87, 102187.

Research output: Contribution to journalArticle

2019

Abaloparatide at the Same Dose Has the Same Effects on Bone as PTH (1-34) in Mice

Le Henaff, C., Ricarte, F., Finnie, B., He, Z., Johnson, J., Warshaw, J., Kolupaeva, V. & Partridge, N. C., Jan 1 2019, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity

Castro, J., Harrington, A. M., Lieu, T. M., Garcia-Caraballo, S., Maddern, J., Schober, G., O'Donnell, T., Grundy, L., Lumsden, A. L., Miller, P., Ghetti, A., Steinhoff, M. S., Poole, D. P., Dong, X., Chang, L., Bunnett, N. W. & Brierley, S. M., Oct 17 2019, In : JCI Insight. 4, 20, e131712.

Research output: Contribution to journalArticle

Open Access

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Ramírez-García, P. D., Retamal, J. S., Shenoy, P., Imlach, W., Sykes, M., Truong, N., Constandil, L., Pelissier, T., Nowell, C. J., Khor, S. Y., Layani, L. M., Lumb, C., Poole, D. P., Lieu, T. M., Stewart, G. D., Mai, Q. N., Jensen, D. D., Latorre, R., Scheff, N. N., Schmidt, B. L. & 5 others, Quinn, J. F., Whittaker, M. R., Veldhuis, N. A., Davis, T. P. & Bunnett, N. W., Dec 1 2019, In : Nature Nanotechnology. 14, 12, p. 1150-1159 10 p.

Research output: Contribution to journalArticle

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

Anderson, B. M., Poole, D. P., Aurelio, L., Ng, G. Z., Fleischmann, M., Kasperkiewicz, P., Morissette, C., Drag, M., van Driel, I. R., Schmidt, B. L., Vanner, S. J., Bunnett, N. W. & Edgington-Mitchell, L. E., Dec 1 2019, In : Scientific reports. 9, 1, 13295.

Research output: Contribution to journalArticle

Open Access

Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride

Li, Y., Liu, Y., Psoter, W. J., Nguyen, O. M., Bromage, T., Walters, M., Hu, B., Rabieh, S. & Kumararaja, F. C., Jan 1 2019, In : Caries Research.

Research output: Contribution to journalArticle

ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

Neginskaya, M. A., Solesio, M. E., Berezhnaya, E. V., Amodeo, G. F., Mnatsakanyan, N., Jonas, E. A. & Pavlov, E. V., Jan 2 2019, In : Cell Reports. 26, 1, p. 11-17.e2

Research output: Contribution to journalArticle

Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model

Wang, S., Wang, N., Yu, B., Cao, M., Wang, Y., Guo, Y., Zhang, Y., Zhang, P., Yu, X., Wang, S., Zeng, L., Liang, B., Li, X. & Wu, Y., Sep 5 2019, In : Oncogene. 38, 36, p. 6338-6353 16 p.

Research output: Contribution to journalArticle

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody

He, S., Fu, Y., Guo, J., Spear, M., Yang, J., Trinité, B., Qin, C., Fu, S., Jiang, Y., Zhang, Z., Xu, J., Ding, H., Levy, D. N., Chen, W., Petricoin, E., Liotta, L. A., Shang, H. & Wu, Y., Jan 1 2019, In : Virginia Law Review. 104, 8, eaat7911.

Research output: Contribution to journalArticle

Comparative Effect of Two Red Lights on Streptococcus mutans Biofilms and Assessment of Temperature Variances in Human Teeth During In Vitro Photodynamic Antimicrobial Chemotherapy

Aragão, M. G. B., Costa, C. A. G. D. A., Lima, R. A., Rodrigues, L. K. A., Duarte, S. & Zanin, I. C. J., Jan 1 2019, In : Photobiomodulation, photomedicine, and laser surgery. 37, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Open Access

Composite materials design: Biomineralization proteins and the guided assembly and organization of biomineral nanoparticles

Evans, J., Feb 15 2019, In : Materials. 12, 4, 581.

Research output: Contribution to journalReview article

Open Access

Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease

Babitt, J. L. & Sitara, D., Jul 1 2019, In : Current opinion in nephrology and hypertension. 28, 4, p. 304-310 7 p.

Research output: Contribution to journalArticle

Daily phototherapy with red light to regulate candida albicans biofilm growth

Panariello, B. H. D., Garcia, B. A. & Duarte, S., Apr 2019, In : Journal of Visualized Experiments. 2019, 146, e59326.

Research output: Contribution to journalArticle

Developmental biology of the meninges

Dasgupta, K. & Jeong, J., Jan 1 2019, In : Genesis. e23288.

Research output: Contribution to journalReview article

Differential regulation of Ca 2+ influx by Orai channels mediates enamel mineralization

Eckstein, M., Vaeth, M., Aulestia, F. J., Costiniti, V., Kassam, S. N., Bromage, T., Pedersen, P., Issekutz, T., Idaghdhour, Y., Moursi, A., Feske, S. & Lacruz, R., Jan 1 2019, In : Science Signaling. 12, 578, aav4663.

Research output: Contribution to journalArticle

Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation

Seidlmayer, L. K., Gomez-Garcia, M. R., Shiba, T., Porter, G. A., Pavlov, E., Bers, D. M. & Dedkova, E. N., Feb 15 2019, In : Archives of Biochemistry and Biophysics. 662, p. 177-189 13 p.

Research output: Contribution to journalArticle

Open Access

Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression

Israelyan, N., Del Colle, A., Li, Z., Park, Y., Xing, A., Jacobsen, J. P. R., Luna, R. A., Jensen, D. D., Madra, M., Saurman, V., Rahim, R., Latorre, R., Law, K., Carson, W., Bunnett, N. W., Caron, M. G. & Margolis, K. G., Aug 2019, In : Gastroenterology. 157, 2, p. 507-521.e4

Research output: Contribution to journalArticle

Effects of the Tobacco Carcinogens N'-Nitrosonornicotine and Dibenzo[a,l]pyrene Individually and in Combination on DNA Damage in Human Oral Leukoplakia and on Mutagenicity and Mutation Profiles in lacI Mouse Tongue

Guttenplan, J., Chen, K. M., Sun, Y. W., Shalaby, N. A. E., Kosinska, W., Desai, D., Gowda, K., Amin, S. & El-Bayoumy, K., Sep 16 2019, In : Chemical research in toxicology. 32, 9, p. 1893-1899 7 p.

Research output: Contribution to journalArticle

G-Protein–Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases

Canals, M., Poole, D. P., Veldhuis, N. A., Schmidt, B. L. & Bunnett, N. W., May 2019, In : Gastroenterology. 156, 6, p. 1600-1616 17 p.

Research output: Contribution to journalReview article

Identification of ZYG11A as a candidate IGF1-dependent protooncogene in endometrial cancer

Achlaug, L., Sarfstein, R., Nagaraj, K., Lapkina-Gendler, L., Bruchim, I., Dixit, M., Laron, Z., Yakar, S. & Werner, H., Jul 1 2019, In : Oncotarget. 10, 43, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

Inhibition of Karyopherin beta 1 suppresses prostate cancer growth

Yang, J., Guo, Y., Lu, C., Zhang, R., Wang, Y., Luo, L., Zhang, Y., Chu, C. H., Wang, K. J., Obbad, S., Yan, W. & Li, X., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Innate αβ T cells mediate antitumor immunity by orchestrating immunogenic macrophage programming

Hundeyin, M., Kurz, E., Mishra, A., Rossi, J. A. K., Liudahl, S. M., Leis, K. R., Mehrotra, H., Kim, M., Torres, L. E., Ogunsakin, A., Link, J., Sears, R. C., Sivagnanam, S., Goecks, J., Islam, K. M. S., Dolgalev, I., Savadkar, S., Wang, W., Aykut, B., Leinwand, J. & 17 others, Diskin, B., Adam, S., Israr, M., Gelas, M., Lish, J., Chin, K., Farooq, M. S., Wadowski, B., Wu, J., Shah, S., Adeegbe, D. O., Pushalkar, S., Vasudevaraja, V., Saxena, D., Wong, K. K., Coussens, L. M. & Miller, G., Jan 1 2019, In : Cancer Discovery. 9, 9, p. 1288-1305 18 p.

Research output: Contribution to journalArticle

Open Access

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

Ran, L., Wang, X., Mi, A., Liu, Y., Wu, J., Wang, H., Guo, M., Sun, J., Liu, B., Li, Y., Wang, D., Jiang, R., Wang, N., Gao, W., Zeng, L., Huang, L., Chen, X., LeRoith, D., Liang, B., Li, X. & 1 others, Wu, Y., Jun 28 2019, In : iScience. 16, p. 106-121 16 p.

Research output: Contribution to journalArticle

Open Access

Low IGF-I Bioavailability Impairs Growth and Glucose Metabolism in a Mouse Model of Human PAPPA2 p.Ala1033Val Mutation

Fujimoto, M., Andrew, M., Liao, L., Zhang, D., Yildirim, G., Sluss, P., Kalra, B., Kumar, A., Yakar, S., Hwa, V. & Dauber, A., Jun 1 2019, In : Endocrinology. 160, 6, p. 1363-1376 14 p.

Research output: Contribution to journalArticle

Low-temperature plasma on peri-implant–related biofilm and gingival tissue

Carreiro, A. F. P., Delben, J. A., Guedes, S., Silveira, E. J. D., Janal, M. N., Vergani, C. E., Pushalkar, S. & Duarte, S., Jan 1 2019, In : Journal of periodontology. 90, 5, p. 507-515 9 p.

Research output: Contribution to journalArticle

Mammalian Taste Cells Express Functional Olfactory Receptors

Malik, B., Elkaddi, N., Turkistani, J., Spielman, A. & Ozdener, M. H., May 29 2019, In : Chemical senses. 44, 5, p. 289-301 13 p.

Research output: Contribution to journalArticle

Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice

Liu, Z., Solesio, M. E., Schaffler, M. B., Frikha-Benayed, D., Rosen, C. J., Werner, H., Kopchick, J. J., Pavlov, E. V., Abramov, A. Y. & Yakar, S., Jan 2019, In : Journal of Bone and Mineral Research. 34, 1, p. 106-122 17 p.

Research output: Contribution to journalArticle

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

Dasgupta, K., Chung, J. U., Asam, K. & Jeong, J., Nov 15 2019, In : Developmental Biology. 455, 2, p. 434-448 15 p.

Research output: Contribution to journalArticle

NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal

Trinité, B., Zhang, H. & Levy, D., Jun 26 2019, In : Retrovirology. 16, 1, 1 p.

Research output: Contribution to journalArticle

Open Access

Non-thermal plasma treatment to enhance the adhesion between enamel surface and orthodontic bracket

Almoammar, S., Alshahrani, I., Asiry, M. A., Duarte, S., Janal, M. & Khoo, E., Jan 1 2019, In : Bio-Medical Materials and Engineering. 30, 4, p. 439-448 10 p.

Research output: Contribution to journalArticle

Novel Nicotine Delivery Systems

Kumar, P. S., Clark, P., Brinkman, M. C. & Saxena, D., Oct 1 2019, In : Advances in dental research. 30, 1, p. 11-15 5 p.

Research output: Contribution to journalReview article

Parathyroid hormone-stimulation of Runx2 during osteoblast differentiation via the regulation of lnc-SUPT3H-1:16 (RUNX2-AS1:32) and miR-6797-5p

Arumugam, B., Vishal, M., Shreya, S., Malavika, D., Rajpriya, V., He, Z., Partridge, N. & Selvamurugan, N., Mar 1 2019, In : Biochimie. 158, p. 43-52 10 p.

Research output: Contribution to journalArticle

Periodontal disease in a young Romanian convenience sample: Radiographic assessment

Hategan, S. I., Kamer, A., Sinescu, C., Craig, R., Jivanescu, A., Gavrilovici, A. M. & Negrutiu, M. L., May 29 2019, In : BMC Oral Health. 19, 1, 94.

Research output: Contribution to journalArticle

Open Access

Positioning a multifunctional basic helix-loop-helix transcription factor within the Ciona notochord gene regulatory network

Kugler, J. E., Wu, Y., Katikala, L., Passamaneck, Y. J., Addy, J., Caballero, N., Oda-Ishii, I., Maguire, J. E., Li, R. & Di Gregorio, A., Apr 15 2019, In : Developmental Biology. 448, 2, p. 119-135 17 p.

Research output: Contribution to journalArticle

Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2

Zhao, P., Pattison, L. A., Jensen, D. D., Jimenez-Vargas, N. N., Latorre, R., Lieu, T., Jaramillo, J. O., Lopez-Lopez, C., Poole, D. P., Vanner, S. J., Schmidt, B. L. & Bunnett, N. W., Jan 1 2019, In : Journal of Biological Chemistry. 294, 27, p. 10649-10662 14 p.

Research output: Contribution to journalArticle

Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice

De Logu, F., Puma, S. L., Landini, L., Portelli, F., Innocenti, A., De Araujo, D. S. M., Janal, M. N., Patacchini, R., Bunnett, N. W., Geppetti, P. & Nassini, R., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5424-5441 18 p.

Research output: Contribution to journalArticle

Open Access

Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain-associated conditions

Roitman, M., Edgington-Mitchell, L. E., Mangum, J., Ziogas, J., Adamides, A. A., Myles, P., Choo-Bunnett, H., Bunnett, N. W. & Gunnersen, J. M., Mar 1 2019, In : Pain Reports. 4, 2, e719.

Research output: Contribution to journalArticle

Open Access

Skeletal development in the sea urchin relies upon protein families that contain intrinsic disorder, aggregation-prone, and conserved globular interactive domains

Pendola, M., Jain, G. & Evans, J., Jan 1 2019, In : PloS one. 14, 10, e0222068.

Research output: Contribution to journalArticle

Open Access

Sophorolipid Biosurfactants Activate Taste Receptor Type 1 Member 3-Mediated Taste Responses and Block Responses to Bitter Taste In Vitro and In Vivo

Ozdener, M. H., Ashby, R. D., Jyotaki, M., Elkaddi, N., Spielman, A., Bachmanov, A. A. & Solaiman, D. K. Y., Jan 1 2019, In : Journal of Surfactants and Detergents.

Research output: Contribution to journalArticle

Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex

Nguyen, A. H., Thomsen, A. R. B., Cahill, T. J., Huang, R., Huang, L. Y., Marcink, T., Clarke, O. B., Heissel, S., Masoudi, A., Ben-Hail, D., Samaan, F., Dandey, V. P., Tan, Y. Z., Hong, C., Mahoney, J. P., Triest, S., Little, J., Chen, X., Sunahara, R., Steyaert, J. & 4 others, Molina, H., Yu, Z., des Georges, A. & Lefkowitz, R. J., Jan 1 2019, (Accepted/In press) In : Nature Structural and Molecular Biology.

Research output: Contribution to journalArticle